
Lacrifill®: cross-linked hyaluronic acid canalicular gel
Lacrifill® is intended for use in adult patients experiencing dry eye symptoms. It is a preservative-free, cross-linked hyaluronic acid canalicular gel for lacrimal occlusion. Each administration of Lacrifill® is proven to provide sustained dry eye relief for up to 6 months.1
While Lacrifill® is generally well tolerated, the most commonly reported adverse event is epiphora (overflow of tears). For a complete list of contraindications and potential adverse events, please consult the Instructions for Use.¹
Ready for your practice
Lacrifill® is a CE-marked and FDA-cleared medical device, supplied in a pre-filled syringe containing 0.6 ml of gel, enough to fully fill both inferior canaliculi of a single patient.¹ It can be administered by trained eyecare professionals in a standard practice setting.¹ Lacrifill® has a 2-year shelf-life and should be stored at room temperature (5–25°C).
Lacrifill® conforms to each patient’s unique canalicular anatomy, eliminating the need for sizing and providing a simple, one-size-fits-all solution. Lacrifill® is designed to support both patient comfort and long-lasting efficacy.1,2

Why peri-operative ocular surface control matters
Dry eye disease can compromise preoperative measurements and surgical planning, increasing the risk of refractive error.3,4 While most patients with pre-existing dry eye are asymptomatic before surgery, 87% become symptomatic after it.5
Managing the ocular surface perioperatively can help maximise surgical outcomes and avoid unsatisfactory vision, worsening symptoms, and patient dissatisfaction.6,7
3 Key Steps
Administration is completed in three key steps. Use the resources below to support administration in clinical practice.
Lacrifill® at ESCRS 2025
Lacrifill® was showcased during the 2025 ESCRS Conference in Copenhagen where two renowned experts, Prof. Benitez del Castillo (Spain) and Dr. Donnenfeld (USA) discussed the importance of managing dry eye in surgery patients and shared the clinical evidence and their experience with Lacrifill®.
View the highlights here, and go to your local Lacrifill® website to see the full video.



















